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Docteur James Schinazi
  • The practice
  • Face
    • Upper face
      • Forehead wrinkles
      • Glabellar wrinkles
      • Crow’s feet wrinkles
      • Hollow temples
      • Eyelids – PlexR ®
      • Medical frontoplasty
    • Mid face
      • Treating hollow undereyes
      • Treating the cheekbones
      • Treating the tear trough
      • Medical rhinoplasty
      • Treating creased cheeks
    • Lower face
      • Lip injections
      • “Barcode” Peri-buccal wrinkles
      • Nasolabial folds
      • Marionette lines
      • Oval of the face and jowls
      • Bruxism and masseter muscle
      • Gummy smile
      • Chin – medical genioplasty
    • Skin quality
      • Mesolift
      • Skinbooster
      • Superficial peel with fruit acids
      • Medium peel
      • Pregnancy mask « Melasma »
      • Silkpeel – Perfectskin
      • Origin Laser
      • Photorejuvenation
      • Rosacea
      • Universkin bespoke serums
  • Our expert treatments
    • Medical profiloplasty
    • Jaw-line « Contouring » or « Texas Filler »
    • Mesopeel: a radiance booster
    • Cristal Fit ® : high intensity medical electrostimulation
    • Cristal® Cryolipolysis
    • Laser hair removal
    • Mesotherpay for the scalp
    • Underarm hyperhidrosis or excessive sweating
  • Injectable products
    • What is hyaluronic acid ?
  • Aesthetic medecine for men
  • News / media
  • Contact us
  • Français
Menu
  • The practice
  • Face
    • Upper face
      • Forehead wrinkles
      • Glabellar wrinkles
      • Crow’s feet wrinkles
      • Hollow temples
      • Eyelids – PlexR ®
      • Medical frontoplasty
    • Mid face
      • Treating hollow undereyes
      • Treating the cheekbones
      • Treating the tear trough
      • Medical rhinoplasty
      • Treating creased cheeks
    • Lower face
      • Lip injections
      • “Barcode” Peri-buccal wrinkles
      • Nasolabial folds
      • Marionette lines
      • Oval of the face and jowls
      • Bruxism and masseter muscle
      • Gummy smile
      • Chin – medical genioplasty
    • Skin quality
      • Mesolift
      • Skinbooster
      • Superficial peel with fruit acids
      • Medium peel
      • Pregnancy mask « Melasma »
      • Silkpeel – Perfectskin
      • Origin Laser
      • Photorejuvenation
      • Rosacea
      • Universkin bespoke serums
  • Our expert treatments
    • Medical profiloplasty
    • Jaw-line « Contouring » or « Texas Filler »
    • Mesopeel: a radiance booster
    • Cristal Fit ® : high intensity medical electrostimulation
    • Cristal® Cryolipolysis
    • Laser hair removal
    • Mesotherpay for the scalp
    • Underarm hyperhidrosis or excessive sweating
  • Injectable products
    • What is hyaluronic acid ?
  • Aesthetic medecine for men
  • News / media
  • Contact us
  • Français

What is hyaluronic acid ?

Hyaluronic acid is a substance naturally produced by our body. It is a sugar whose synthesis inexplicably lowers over time.

This polysaccharide is a major agent for skin hydration thanks to its hydrophilia (ability to attract water). It is broken down by the intracellular enzymatic system (hyaluronidase) and free radicals (stress, lack of sleep, smoking, sun exposure).

The skin’s hydration therefore depends on the balance between the synthesis of hyaluronic acid (which attracts water) and the action of the endogenous hyaluronidases (which break down the hyaluronic acid).

As we age, this balance changes and the hyaluronidases start to win the battle, and what is more, the quality of the hyaluronic acid produced goes down.

The result, to varying degrees, is:

  • Skin dryness
  • Dermal atrophy (the skin becomes thinner)
  • Wounds take longer to heal
  • An increased risk of developing stretch marks


In women, after the menopause, the drop in hormones (primarily progesterone and oestrogen) leads to a more significant drop in hyaluronic acid synthesis in the dermis than in men.

Properties of hyaluronic acid

Hyaluronic acid boasts a number of properties, among which are:

  • Considerable hydrophilia: one molecule of hyaluronic acid can attract up to 1,000 water molecules, which means it has powerful hydrating, filling and natural volumising properties
  • Remarkable viscosity and elasticity
  • An antioxidant action because free radicals are trapped inside the hyaluronic acid molecule, meaning it plays a role in slowing down skin aging
  • It acts as a barrier against viral and bacterial aggressions  

Hyaluronic acid and aesthetic medicine

Today, aesthetic medicine in France must, above all, be safe.

Hyaluronic acid injections are the ultimate medical tool because they are completely resorbable and biodegradable over time.

These “fillers” are designed to last longer than endogenous hyaluronic acid (made by the body), namely thanks to the process that cross-links the molecules during manufacture. 

Indications for optimum results

The amount of time these injectables last depends on the product used, the areas injected and the indications:

For skin hydration

Skinboosters, mesolift: the hyaluronic acid used is weakly cross-linked, the molecules are small and are very hydrophilic.

On average, the effects last 3 to 6 months.

The main indications are creased cheeks, peri-buccal wrinkles (“barcode” lines) and a loss of firmness in the face.

The injections are pain-free and are performed into the superficial layers, yet the product is not visible to the naked eye. The “fresh-faced” appearance is almost instantaneous.  

For filling wrinkles

The hyaluronic acid used is specially made and designed to fill fine lines, deep wrinkles and hollows. These fillers tend to last longer, generally around 9 months to 1 year.

The main indications are injections into the nasolabial folds, expression lines, lips, tear trough and under-eye circles.

Note that the under-eye area is slightly different because the product used is still hyaluronic acid but this time it is synthesised and shaped so as to reduce its hydrophilia as much as possible to avoid causing bags to appear around the eyes.

Furthermore, since this area of the face has very low levels of endogenous hyaluronidase, this means that the product lasts longer: one or sometimes two years.

For restoring volumes

“Volumising” hyaluronic acid is essentially made up of large molecules so it allows us to create better and more natural projection in the deep structures that have started to sag over time.

The main indications are the cheekbones, the tear trough, the chin, the cheeks and the temples.

The effects last 12 months on average, sometimes more if the patient has a healthy lifestyle (no smoking, no sun or UV exposure, proper hydration, etc.).
Whatever the indication, the results are visible immediately after the hyaluronic acid injections and improve by around 30% in the month that follows (since they draw water to and therefore hydrate the areas treated).

Counterindications for hyaluronic acid injections

Before any hyaluronic acid injections, your doctor must rule out any possible counterindications for this type of treatment, which are:

  • Local ailment in the area to be injected (wound that is healing, cold sore, etc.)
  • A history of non-resorbable filler injections (Aquamid, silicone, etc.) in the area to be treated
  • A history of autoimmune disease (Graves’ disease, Hashimoto’s disease, Lupus, scleroderma, ankylosing spondylitis, rheumatoid arthritis, etc.)


These temporary or permanent counterindications are evaluated case by case in your first appointment with your aesthetics doctor, who will examine your skin after asking you about your medical and surgical history.

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11, avenue Raymond Poincaré
75116 Paris

The practice is on the ground floor, on the right
Tél : 01 56 62 10 77

contact@docteur-schinazi.com

Parking nearby

Metro ligne 6 et 9 Trocadéro
Bus 22, 32, 63, 82

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Medical order registration number: 75/80370

Member of a certified management association